Angew. Chem. Int. Ed. 2006, 45 (10), 1544- 1548

Solving the clogging problem: Precipitate-forming reactions in flow

Angew. Chem. Int. Ed. 2006, 45 (10), 1544- 1548

Poe SL, Cummings MA, Haaf MR, McQuade DT


Solids go with the flow: A monodisperse flow in a microreactor provides an efficient method for keeping solid products away from channel walls. The use of a carrier phase, such as mineral oil, hexane, or toluene, enables solids to be synthesized without clogging of the reactor channels. Further injection points can be added to the microreactor to perform multistep syntheses (see picture).